Sanfew serum(4)

A 4 dose Sanfew Serum.

MembersBuy limit 2,000Potions & Drinks

Wiki

Insta-buyHighest recent buy

22,751gp

Insta-sellLowest recent sell

22,204gp

SpreadBefore tax

547gp

2.46%

MarginAfter 2% GE tax

+92gp

+0.41% ROI

VolumeTraded in 30D

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TrendMid price, 30D

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Price history

1 points · hover for detail

Insta-buy (high)Insta-sell (low)Spread

Volume · units traded

30D low: 22,204
30D high: 22,751
Volatility: 2.4%

Flip calculator

Includes the 2% Grand Exchange tax

Buy at

Sell at

Quantity

units

Net profitProfitable

+92gp

+92 per item · +0.41% ROI

Capital required: 22,204 gp
Gross revenue: 22,751 gp
GE tax (2%, 455/item): − 455 gp
Break-even sell: 22,657 gp

Item data

High alchemy: 180 gp99.2% below market
Low alchemy: 120 gp
Shop value: 300 gp
Weight: 0.035 kg
Skill / type: Herblore
Requires: Herblore 65
Stack / note: Not stackable · noteable
Released: Mar 13, 2007

About Sanfew serum(4)

The Sanfew serum(4) is a members-only potion in Old School RuneScape.

"A 4 dose Sanfew Serum"

Over the last 30 days it traded between 19,147 and 22,707 gp on the Grand Exchange, averaging 20,435 gp. About 160,364 units changed hands per day. The price is up 18.1% across that window. The Grand Exchange buy limit is 2,000 every 4 hours. Selling one at the average price costs 408 gp in Grand Exchange tax.

Casting High Level Alchemy returns 180 gp, which is 99.1% below the 30-day average price, so alching a bought one loses money.

How to get Sanfew serum(4)

7 monsters drop Sanfew serum(4), most commonly Coffin (Hallowed Sepulchre) (1/10), Grand Hallowed Coffin (1/10) and Hallowed sack (1/10). It can be made from Mixture - step 2(4) and Nail beast nails.

Dropped by

Monster	Rarity	Quantity
Coffin (Hallowed Sepulchre)	1/10	1–2
Grand Hallowed Coffin	1/10	1–2
Hallowed sack	1/10	1–2
Vet'ion	5/126	20 (noted)
Calvar'ion	5/128	6 (noted)
Kraken	4/128	2
Thermonuclear smoke devil	3/107	2

Recipes

Where this item appears in crafting and processing.

Made from

1× Mixture - step 2(4), 1× Nail beast nails

Sanfew serum(4) price history

Daily averages rolled up per month, newest first.

Monthly average, low and high price of Sanfew serum(4) on the Grand Exchange
Month	Average	Low	High	Volume
October 202612d	21,572	19,575	22,707	2,482,291
September 2026	19,334	18,120	20,651	4,067,833
August 2026	20,429	17,977	21,345	4,432,136
July 2026	20,532	19,140	21,734	6,562,391
June 202621d	21,011	19,240	22,724	2,474,836
May 20262d	18,551	18,015	19,087	161,393
April 20261d	17,900	17,900	17,900	54,500
March 2026	21,238	19,672	22,784	1,081,673
February 2026	18,851	17,579	19,907	147,000
January 2026	15,007	13,904	16,947	17,856

Across 10 months of recorded prices Sanfew serum(4) ranged from 13,904 gp in January 2026 to 22,784 gp in March 2026, measured over 218 trading days.

The 30-day average of 20,435 gp sits in the upper third of that range.

All prices in gp. Volume counts units traded across both sides of the Grand Exchange.

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